ncRNA name | hsa-miR-433 |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | human RB cell lines Y79 and WERI-RB1 |
Methods | qRT-PCR, luciferase reporter assay, transfection, MTT assay, Western blot |
Expression pattern | down-regulated |
Functional description | miR-433 negatively regulated RB cell proliferation, migration and invasion, and induced cell cycle arrest and apoptosis of RB cells. miR-433 regulates RB cell proliferation and metastasis through suppressing the expression of Notch1 and PAX6. |
PubMed ID | 27470361 |
Year | 2016 |
Title | MiR-433 inhibits retinoblastoma malignancy by suppressing Notch1 and PAX6 expression. |
Drug-related ncRNA | NO |
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